{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:08:45Z","timestamp":1777946925246,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T00:00:00Z","timestamp":1231459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T00:00:00Z","timestamp":1231459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"abstract":"<jats:p>The influence of assisted ventilation by means of a respirator on arterial oxygen and carbon dioxide tensions was studied in 20 patients with chronic respiratory failure, caused by chronic non-specific lung disease.It was found that during respirator induced hyperventilation, causing the fall of PaCO&lt;sub&gt;2&lt;\/sub&gt;, PaO&lt;sub&gt;2&lt;\/sub&gt; fell in most patients. The fall of PaO&lt;sub&gt;2&lt;\/sub&gt; was more pronounced when high positive pressure was applied. The adding of slight negative pressure during the expiratory phase prevented to some extent the fall of PaO&lt;sub&gt;2&lt;\/sub&gt;.Using O&lt;sub&gt;2&lt;\/sub&gt;-CO&lt;sub&gt;2&lt;\/sub&gt; diagram it was possible to demonstrate that in most patients hyperventilation was connected with the increase of alveolar-arterial oxygen tension difference. Mechanisms that might play a role in increasing of alveolar-arterial oxygen tension difference are discussed.<\/jats:p>","DOI":"10.1159\/000192679","type":"journal-article","created":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T08:34:25Z","timestamp":1231490065000},"page":"162-175","source":"Crossref","is-referenced-by-count":0,"title":["Oxygen Tension in Arterial Blood During Assisted Ventilation in Patients with Chronic Respiratory Failure"],"prefix":"10.1159","author":[{"given":"J.","family":"Zieli\u0144ski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,9]]},"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/192679","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000192679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T20:54:09Z","timestamp":1777755249000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000192679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000192679","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,9]]}}}