{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:08:48Z","timestamp":1777946928270,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T00:00:00Z","timestamp":1231459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T00:00:00Z","timestamp":1231459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"abstract":"<jats:p>Light and electron microscopic studies on the main stem bronchus as well as on lobar and segmental bronchi of short (6\u201320 days) and long- term (5\u20136 years) autografted canine lungs yielded the following results. All nerve fibers deriving from extrapulmonary ganglion cells were transected during the transplantations and consequently underwent Wallerian degeneration. The intrapulmonary neurons survive in short-term lung transplants but they show marked regressive alterations and a reduction in number in long-term transplants. No effective nerve regeneration at the site of bronchial anastomosis could be detected. Further investigations on NA content and NA uptake in bronchial walls of short-term and long-term grafts supported the morphological findings, namely, that a number of adrenergic neurons of the intrapulmonary bronchial plexus survive. At the site of lobar and segmental bronchi in short-term grafts the NA uptake was found to be higher than in identical portions of the control lungs. These findings were interpreted as a result of a retarded NA release due to decentralization of neurons. However, in long-term transplants a reduction of NA uptake could be demonstrated at the site of lobar bronchi. This is in accordance with the morphological findings which proved regressive alterations in the intrapulmonary neurons.<\/jats:p>","DOI":"10.1159\/000193027","type":"journal-article","created":{"date-parts":[[2009,1,9]],"date-time":"2009-01-09T08:34:25Z","timestamp":1231490065000},"page":"117-126","source":"Crossref","is-referenced-by-count":0,"title":["The Adrenergic Innervation of Bronchi in Autotransplanted Canine Lungs"],"prefix":"10.1159","author":[{"given":"S.","family":"Bl\u00fcmcke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Dellschau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.","family":"Dengler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nasseri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Eisele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"K\u00f6tter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,9]]},"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/193027","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000193027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T20:58:24Z","timestamp":1777755504000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000193027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000193027","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,9]]}}}