{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T16:18:41Z","timestamp":1789057121615,"version":"build-2803163510"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T00:00:00Z","timestamp":1231977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T00:00:00Z","timestamp":1231977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"abstract":"<jats:p>We assessed ventilatory responses of 8 women to chronic contraceptive pill administration. We also studied 5 non-pill-taking women to determine if our techniques were capable of detecting the known ventilatory changes in the luteal phase of the menstrual cycle. During the high-progestin phase, relative to the low-progestin phase, the pill group had a mean increase in slope of CO&lt;sub&gt;2&lt;\/sub&gt; response of 0.78 litres\/min\/mm Hg, a mean decrease in resting PET&lt;sub&gt;CO2&lt;\/sub&gt; of 1.3 mm Hg, and no change in hypoxic sensitivity. The non-pill group had no change in slope of CO&lt;sub&gt;2&lt;\/sub&gt; response, a mean decrease in resting Pet&lt;sub&gt;CO2&lt;\/sub&gt; of 1.1 mm Hg, and no change in hypoxic sensitivity. We conclude that the contraceptive pills studied cause a slight hyperventilation that is probably mediated by a central mechanism, as no changes in peripheral response were detected.<\/jats:p>","DOI":"10.1159\/000194483","type":"journal-article","created":{"date-parts":[[2009,1,31]],"date-time":"2009-01-31T10:30:40Z","timestamp":1233397840000},"page":"179-185","source":"Crossref","is-referenced-by-count":10,"title":["Ventilatory Response of Humans to Chronic Contraceptive Pill Administration"],"prefix":"10.1159","author":[{"given":"Curtis A.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan H.","family":"Mines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,1,15]]},"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/194483","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000194483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T21:10:57Z","timestamp":1777756257000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000194483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,15]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000194483","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,15]]}}}