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Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Surg Res"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; In this study the potential of a new and entirely synthetic, nano-structured hydroxyapatite-based biomaterial for sinus floor augmentation is evaluated. &lt;i&gt;Methods:&lt;\/i&gt; 20 sinus floor elevations were carried out in a total of 20 patients. After a healing period of 6 months, in 10 cases cylinder-shaped bone biopsies were taken from the augmented maxillary region using trephine burs. &lt;i&gt;Results:&lt;\/i&gt; The healing period progressed without any complications. General and specific histological analysis of the bone biopsies showed a high osteoclast activity at the margin of the biomaterial which was well integrated into the newly formed bone. &lt;i&gt;Conclusion:&lt;\/i&gt; This study demonstrates that new trabecular bone is formed after grafting with the nanocrystalline bone substitute after 6 months. Ongoing histomorphological studies are necessary to quantify the biomaterial-bone ratio and the exact amount of newly built bone in the augmented cavity after 6 months.<\/jats:p>","DOI":"10.1159\/000197215","type":"journal-article","created":{"date-parts":[[2009,1,31]],"date-time":"2009-01-31T15:42:55Z","timestamp":1233416575000},"page":"143-149","source":"Crossref","is-referenced-by-count":17,"title":["Maxillary Sinus Grafting with a Nano-Structured Biomaterial: Preliminary Clinical and Histological Results"],"prefix":"10.1159","volume":"42","author":[{"given":"S.","family":"St\u00fcbinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ghanaati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Orth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Hilbig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Saldamli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Biesterfeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.J.","family":"Kirkpatrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.A.","family":"Sader","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00005131-198909000-00002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1708-8208.2007.00050.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS1079-2104%2898%2990029-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.joms.2004.01.009"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fjbm.b.30015"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2Fterm.11"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.injury.2005.07.029"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TP.0000107283.19336.DA"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1902%2Fjop.2002.73.3.266"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0501.2007.01494.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2Fjbm.820050613"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0501.1997.080606.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2F0142-9612%2896%2985915-1"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-051x.2000.027011799.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10006-004-0561-9"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1902%2Fannals.2003.8.1.328"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0501.2002.130613.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0501.2007.01487.x"}],"container-title":["European Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/197215","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/197215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:38:06Z","timestamp":1745451486000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000197215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000197215","archive":["Portico"],"relation":{},"ISSN":["0014-312X","1421-9921"],"issn-type":[{"type":"print","value":"0014-312X"},{"type":"electronic","value":"1421-9921"}],"subject":[],"published":{"date-parts":[[2009]]}}}