{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:39:03Z","timestamp":1777865943273,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,23]],"date-time":"2009-01-23T00:00:00Z","timestamp":1232668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,23]],"date-time":"2009-01-23T00:00:00Z","timestamp":1232668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"abstract":"<jats:p>The period of the pacesetter potentials (PP) in the normal human stomach was studied when infusing HCl (75 mEq\/l) or saline in the stomach or duodenum. When a 350-ml volume of saline was infused into the stomach, an 11 % increase of the PP period was observed. With 350 ml of acid solution, the maximum increase was 40%. This occurred 8 min after the onset of infusion, at the moment when the serum gastrin level was significantly lowered. When the acid solution was infused into the duodenum, a flow rate of acid dependent increase of the PP period occurred (43% with 4 ml\/min). Saline induced no change. A single intravenous injection of secretin (0.5 U\/kg) induced an increase in the PP period whose maximum (35%) occurred 4 min after the injection. The results suggest that gastric myoelectrical activity may be affected by a hormonal regulation in which endogenous secretin and gastrin would determine opposite responses.<\/jats:p>","DOI":"10.1159\/000197479","type":"journal-article","created":{"date-parts":[[2009,1,26]],"date-time":"2009-01-26T10:51:04Z","timestamp":1232967064000},"page":"502-513","source":"Crossref","is-referenced-by-count":6,"title":["Effects of Acid in Stomach and Duodenum upon the Gastric Myoelectrical Activity in Man"],"prefix":"10.1159","author":[{"given":"D.","family":"Couturier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Roz\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Vasconcellos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.P.","family":"Accary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Debray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,23]]},"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/197479","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000197479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:44:05Z","timestamp":1777535045000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000197479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000197479","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,23]]}}}