{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:39:25Z","timestamp":1777865965417,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,23]],"date-time":"2009-01-23T00:00:00Z","timestamp":1232668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,23]],"date-time":"2009-01-23T00:00:00Z","timestamp":1232668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"abstract":"<jats:p>2-Deoxy-D-glucose (2-DG), a potent vagal stimulator, is used for testing the completeness of surgical vagotomies. 2-DG has however not yet been employed routinely for the postoperative testing of vagotomized patients because of possible cardiotoxic effects. In a previous study, we have shown the effects of 2-DG on the resting ECG in 48 patients. We did not observe any significant changes besides nonspecific T wave flattening and QT prolongation. The present investigation included 37 additional patients. In 27 patients, a continuous ECG tape recording for detection of arrhythmias was performed and in 10 patients, the systolic time intervals for non-invasive assessment of the myocardial contractility was recorded before and after 2-DG. Serious arrhythmias were not provoked by 2-DG. Premature contractions were, as a whole, not increased by the drug. 2-DG did not have any cardiodepressive action. On the contrary myocardial contractility evaluated by the systolic time intervals was enhanced.<\/jats:p>","DOI":"10.1159\/000197647","type":"journal-article","created":{"date-parts":[[2009,1,26]],"date-time":"2009-01-26T09:24:49Z","timestamp":1232961889000},"page":"1-8","source":"Crossref","is-referenced-by-count":6,"title":["Cardiac Changes during 2-Deoxy-D-Glucose Test"],"prefix":"10.1159","author":[{"given":"Dieter","family":"Burckhardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg A.","family":"Stalder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,23]]},"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/197647","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000197647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:45:17Z","timestamp":1777535117000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000197647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000197647","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,23]]}}}