{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:40:21Z","timestamp":1777866021795,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,1,27]],"date-time":"2009-01-27T00:00:00Z","timestamp":1233014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,1,27]],"date-time":"2009-01-27T00:00:00Z","timestamp":1233014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"abstract":"<jats:p>The interrelations of meal stimulated gastrin release, antral gastrin concentration (AGC) and acid secretion rate were examined in a heterogenous group of 72 patients. Gastrin release calculated as the integrated gastrin output was directly related to AGC, r = 0.50 (p &lt; 0.001) and inversely related to maximum acid output (MAO), r = -0.31 (p &lt; 0.01). The relation between integrated gastrin output and AGC was significant in 21 patients with low acid secretion rates (MAO: &lt; 10 mEq\/h), r = 0.66 (p &lt; 0.01) and in 27 patients with normal acid secretion rates (MAO: 10\u201325 mEq\/h), r = 0.56 (p &lt; 0.05), but not in 24 patients with high acid secretion rates (MAO: &gt; 25 mEq\/h), r = 0.35 (p &gt; 0.05). A weak inverse relation between AGC and MAO may exist in patients with low acid secretion rates, r = -0.40 (p &lt; 0.10). Considered together using multiple regression procedures AGC and MAO explained less than one-half of the variability in meal stimulated gastrin release.<\/jats:p>","DOI":"10.1159\/000198105","type":"journal-article","created":{"date-parts":[[2009,1,31]],"date-time":"2009-01-31T12:11:36Z","timestamp":1233403896000},"page":"151-158","source":"Crossref","is-referenced-by-count":6,"title":["The Interrelations of Gastrin Release, Antral Gastrin Concentration and Acid Secretion Rate"],"prefix":"10.1159","author":[{"given":"W.S.","family":"Hughes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Wharton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,1,27]]},"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/198105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000198105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:51:23Z","timestamp":1777535483000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000198105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000198105","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1,27]]}}}