{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:14:01Z","timestamp":1761894841553,"version":"3.40.4"},"reference-count":37,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Dietary intake of wheat causes hypersensitivity reactions in patients suffering from IgE-mediated food allergy and coeliac disease. &lt;i&gt;Aim:&lt;\/i&gt; To study the expression of IgE- and IgA-reactive antigens during wheat seed maturation and in different wheat cultivars. &lt;i&gt;Methods:&lt;\/i&gt; Summer wheat was grown in a glasshouse and seeds were harvested at defined maturation stages. Mature seeds were obtained from 13 different defined cultivars. Protein extracts were prepared from different maturation stages and cultivars with a standardized procedure based on seed weight and analysed by IgE and IgA immunoblotting using sera from clinically defined patients suffering from wheat allergy or coeliac disease. &lt;i&gt;Results:&lt;\/i&gt; With a few exceptions the expression of IgE- and IgA-reactive wheat antigens increased during wheat seed maturation. Wheat cultivars could be identified in which the expression of certain IgE- and IgA-reactive components was strongly reduced or not detectable. &lt;i&gt;Conclusions:&lt;\/i&gt; The expression of IgE- and IgA-reactive antigens depends on wheat seed maturation and varies in different wheat cultivars.<\/jats:p>","DOI":"10.1159\/000199713","type":"journal-article","created":{"date-parts":[[2009,2,12]],"date-time":"2009-02-12T23:46:37Z","timestamp":1234482397000},"page":"181-187","source":"Crossref","is-referenced-by-count":5,"title":["Detection of Antigens Reactive to IgE and IgA during Wheat Seed Maturation and in Different Wheat 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