{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T17:38:20Z","timestamp":1777743500103,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,2,17]],"date-time":"2009-02-17T00:00:00Z","timestamp":1234828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,2,17]],"date-time":"2009-02-17T00:00:00Z","timestamp":1234828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"abstract":"<jats:p>Erythropoietin levels were determined in 50 Greek females: 20 beta-thalas-saemia (beta-thai) heterozygotes, 15 with a diagnosis of iron-deficiency anaemia and 15 normal controls. In beta-thai trait carriers, the erythropoietin levels were slightly higher than in normal controls (16.65 \u00b1 4.43 vs. 12.84 \u00b1 2.47 mU\/ml); these levels were significantly lower than those in iron-deficient subjects with the same degree of anaemia (55.24 \u00b1 31.35 mU\/ml). In both groups, the erythropoietin levels are statistically correlated with the severity of anaemia (r = -0.537 p &lt; 0.05 for iron deficiency; r = -0.610 p &lt; 0.01 for beta-thai heterozygotes). In beta-thai heterozygotes, a close inverse correlation with red cell number and erythropoietin levels was also noted. It is suggested that microcytosis accompanying beta-thai trait constitutes an additional factor intervening in the regulation of erythropoiesis.<\/jats:p>","DOI":"10.1159\/000203609","type":"journal-article","created":{"date-parts":[[2009,2,18]],"date-time":"2009-02-18T15:14:43Z","timestamp":1234970083000},"page":"147-149","source":"Crossref","is-referenced-by-count":12,"title":["Erythropoietin Levels and Microcytosis in Heterozygous Beta-Thalassaemia"],"prefix":"10.1159","author":[{"given":"T.","family":"Tassiopoulos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Konstantopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Tassiopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Rombos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Alevizou-Terzaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Kyriaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Loukopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,2,17]]},"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/203609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000203609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:35:41Z","timestamp":1777462541000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000203609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000203609","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2,17]]}}}