{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:55:56Z","timestamp":1780631756801,"version":"3.54.1"},"reference-count":14,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aims:&lt;\/i&gt; The study was undertaken to understand the characteristic of plasma cell leukemia (PCL) in China. &lt;i&gt;Methods:&lt;\/i&gt; We reviewed and compared medical data of 22 primary PCL, 9 secondary PCL and 461 multiple myeloma (MM) diagnosed at our institute from January 2000 to January 2008. &lt;i&gt;Results:&lt;\/i&gt; The median onset ages of primary and secondary PCL patients were 49.5 and 56 years, respectively. PCL patients presented with a low peripheral blood plasmacytosis, extensive involvement of visceral organs and poor residual bone marrow function, without severe renal insufficiency. Seventeen of twenty-one PCL patients had abnormal karyotypes, mostly complex and hypodiploid or pseudodiploid. The deletion of 13q was frequent in primary and secondary PCL (57.1 and 42.9%, respectively). There was a significant difference in survival among primary PCL, secondary PCL and MM (median 14, 2 and 37 months, respectively, p = 0.0000). &lt;i&gt;Conclusion:&lt;\/i&gt; Overall, primary and secondary PCL are different disorders with distinct natural histories and survival.<\/jats:p>","DOI":"10.1159\/000210555","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T14:14:27Z","timestamp":1238681667000},"page":"47-51","source":"Crossref","is-referenced-by-count":29,"title":["A Retrospective Analysis of Thirty-One Cases of Plasma Cell Leukemia from a Single Center in China"],"prefix":"10.1159","volume":"121","author":[{"given":"Qi","family":"Peijing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Yafei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zou","family":"Dehui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zengjun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Junyuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Yaozhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu","family":"Lugui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,4,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.133.5.813"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9343%2887%2990942-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2141.1994.tb05114.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood.V97.3.822"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038%2Fleu.2008.4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00277-002-0480-5"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.leukres.2008.06.027"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000109470"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.leu.2401211"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs11864-001-0034-4"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2Fajh.20272"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.bmt.1700982"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.leukres.2008.03.013"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.22700"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/210555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/210555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:51:17Z","timestamp":1745448677000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000210555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000210555","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}