{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:47:44Z","timestamp":1745470064738,"version":"3.40.4"},"reference-count":27,"publisher":"S. Karger AG","issue":"Suppl. 1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>We report a case of eosinophilic pneumonia that was successfully treated with suplatast tosilate. A 72-year-old woman with hypertension and diabetes, who did not smoke and did not have pets, consulted a physician with the chief complaints of cough, sputum, and slight fever. Chest X-ray films revealed a permeation shadow in the bilateral upper lobes. She visited a hospital because her symptoms did not improve. Pulmonary tuberculosis was suspected because of an elevated inflammatory reaction, and anti-tuberculosis treatment was started. Afterwards, eosinophilia appeared in the peripheral blood. Although daily drugs (nicardipine hydrochloride, pentoxifylline, and ticlopidine hydrochloride) were stopped, eosinophilia did not improve and was detected in a sputum sample. She was diagnosed with pulmonary infiltration with eosinophilia syndrome and hospitalized. Physical examination revealed neither rhonchus nor cardiac murmurs on auscultation. Laboratory findings showed a leukocyte count of 21,300\/\u03bcl, with eosinophils accounting for 66.3% of cells. A diagnosis of eosinophilic pneumonia was made after a lung biopsy specimen was examined under a bronchial fiberscope. After suspension of anti-tuberculosis drugs and administration of suplatast tosilate 300 mg\/day for 4 weeks, symptoms subsided, eosinophilia improved to within normal ranges, eosinophils in sputum disappeared, and the permeation shadow disappeared on chest X-ray films.<\/jats:p>","DOI":"10.1159\/000211380","type":"journal-article","created":{"date-parts":[[2009,6,2]],"date-time":"2009-06-02T12:42:59Z","timestamp":1243946579000},"page":"94-101","source":"Crossref","is-referenced-by-count":1,"title":["A Case of Eosinophilic Pneumonia Successfully Treated with Suplatast Tosilate Alone"],"prefix":"10.1159","volume":"149","author":[{"given":"Naoto","family":"Watanabe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohei","family":"Makino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,6,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fthx.7.1.1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.03.00085603"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159%2F000088008"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.111.6.1767"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1440-1843.2001.00297.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1254%2Fjjp.61.23"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1254%2Fjjp.61.31"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0024-3205%2895%2900132-P"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1081%2FJAS-120004925"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2003.1415"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1081%2FJAS-100000041"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2332%2Fallergolint.O-06-478"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.105.5.1462"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2169%2Finternalmedicine.39.830"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM196904102801501"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Fthx.35.8.570"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.103.1.162"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F00005792-198805000-00002"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2005.00812.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.2468%2Fjbes.52.259"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.102.4.1296"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.2005.00897.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016%2FS1567-5769%2801%2900142-4"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2222.2001.01241.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00228-002-0468-z"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2222.2002.01547.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2006.02616.x"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/211380","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/211380","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:59:50Z","timestamp":1745449190000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000211380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":27,"journal-issue":{"issue":"Suppl. 1","published-online":{"date-parts":[[2009,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000211380","archive":["Portico"],"relation":{},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"type":"print","value":"1018-2438"},{"type":"electronic","value":"1423-0097"}],"subject":[],"published":{"date-parts":[[2009]]}}}