{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:14:40Z","timestamp":1772748880408,"version":"3.50.1"},"reference-count":13,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background\/Aims: &lt;\/i&gt;The aim of this meta-analysis was to determine whether frozen embryo transfer (ET) increases ectopic pregnancy (EP) rate compared with fresh ET. &lt;i&gt;Methods:&lt;\/i&gt; A meta-analysis was performed of data from seven comparative studies including 13,059 pregnancies that resulted from nondonor in vitro fertilization cycles. &lt;i&gt;Results:&lt;\/i&gt; The EP rate was 2.31% (49\/2,125 pregnancies) for frozen ET and 1.48% (162\/10,934 pregnancies) for fresh ET. These rates were statistically not different when assessed either by random (OR 1.66, 95% CI 0.62\u20134.41) or fixed effect model (OR 1.17, 95% CI 0.84\u20131.63). &lt;i&gt;Conclusions:&lt;\/i&gt; The combined data presented in this meta-analysis do not support an increased risk of EP following frozen ET compared with fresh ET. However, as there was a substantial heterogeneity among the studies analyzed, the authors consider that further well-designed studies controlling for several potential biases which could affect the EP risk should be conducted.<\/jats:p>","DOI":"10.1159\/000213048","type":"journal-article","created":{"date-parts":[[2009,4,16]],"date-time":"2009-04-16T15:28:57Z","timestamp":1239895737000},"page":"53-57","source":"Crossref","is-referenced-by-count":19,"title":["Ectopic Pregnancy Rates after Frozen versus Fresh Embryo Transfer: A Meta-Analysis"],"prefix":"10.1159","volume":"68","author":[{"given":"Byung Chul","family":"Jee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Suk","family":"Suh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0015-0282%2899%2900226-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0015-0282%2898%2900441-5"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00001703-200010000-00005"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02215992"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080%2F01443619867137"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0015-0282%2802%2903749-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0015-0282%2803%2901372-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.fertnstert.2006.12.005"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.fertnstert.2006.11.169"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumrep%2F16.6.1115"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2393-3-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.fertnstert.2003.10.042"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumrep%2F10.1.199"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/213048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/213048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:08:38Z","timestamp":1745446118000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000213048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000213048","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}