{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:21:38Z","timestamp":1777929698034,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,17]],"date-time":"2009-04-17T00:00:00Z","timestamp":1239926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,17]],"date-time":"2009-04-17T00:00:00Z","timestamp":1239926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Seit der Entdeckung eines sehr hohen Bluthistaminspiegels bei der chronischen myeloischen Leuk\u00e4mie (CML) 1936 konnte der Autor nachweisen, da\u00df dieser Parameter bei der Differentialdiagnose zwischen CML und verschiedenen \u00bbleuk\u00e4moiden\u00ab Reaktionen, bei der Fr\u00fchdiagnose der CML sowie bei der Differentialdiagnose zwischen CML und anderen myeloproliferativen Erkrankungen sehr wertvoll ist. Neuere Untersuchungen haben erwiesen, da\u00df zwischen Bluthistaminspiegel und Basophilenzahl im peripheren Blut keine Korrelation besteht. Weitere Untersuchungen sollen die Frage beantworten, ob es m\u00f6glich ist, durch laufende Kontrolle des Bluthistaminspiegels den \u00dcbergang einer Polycythaemia vera in eine CML vorauszusagen oder festzustellen, ob einer Osteomyelosklerose eine CML vorausgegangen ist.<\/jats:p>","DOI":"10.1159\/000214474","type":"journal-article","created":{"date-parts":[[2009,4,20]],"date-time":"2009-04-20T11:36:39Z","timestamp":1240227399000},"page":"70-74","source":"Crossref","is-referenced-by-count":1,"title":["Der Bluthistaminspiegel bei chronischen myeloproliferativen Erkrankungen \u2013 Ein \u00dcberblick"],"prefix":"10.1159","author":[{"given":"N.","family":"Gingold","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,17]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/214474","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000214474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:48:52Z","timestamp":1777679332000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000214474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000214474","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,17]]}}}