{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:23:45Z","timestamp":1777929825835,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T00:00:00Z","timestamp":1240272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T00:00:00Z","timestamp":1240272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Bei 20 Patienten mit Karzinomen im Kopf-Hals-Bereich ist die Dunkeladaptation verz\u00f6gert. Die Patienten haben gegen\u00fcber gesunden Kontrollen signifikant niedrigere Serum-Vitamin-A-Spiegel. Da ein Vitamin-A-Mangel erst nach l\u00e4ngerer Zeit seines Bestehens zu einer Verz\u00f6gerung der Dunkeladaptation f\u00fchrt, wird angenommen, da\u00df das Defizit schon l\u00e4ngere Zeit bestanden hat. Aufgrund der antineoplastischen Potenz des Vitamins k\u00f6nnte diesem Umstand eine Bedeutung bei der Entstehung und dem Wachstum der Tumoren zukommen. Die Ursache f\u00fcr den gest\u00f6rten Vitamin-A-Stoffwechsel liegt m\u00f6glicherweise in einer langdauernden Fehlem\u00e4hrung.<\/jats:p>","DOI":"10.1159\/000215255","type":"journal-article","created":{"date-parts":[[2009,4,22]],"date-time":"2009-04-22T10:40:22Z","timestamp":1240396822000},"page":"314-318","source":"Crossref","is-referenced-by-count":1,"title":["Zur Dunkeladaptation bei Patienten mit Tumoren im Kopf-Hals-Bereich"],"prefix":"10.1159","author":[{"given":"E.","family":"Bichler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Daxecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,21]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/215255","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000215255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:54:51Z","timestamp":1777679691000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000215255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,21]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000215255","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,21]]}}}