{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:24:09Z","timestamp":1777929849716,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T00:00:00Z","timestamp":1240272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,21]],"date-time":"2009-04-21T00:00:00Z","timestamp":1240272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Es wird \u00fcber einen 44j\u00e4hrigen Patienten mit einem Kappa-Leichtket-tenplasmozytom berichtet, welcher bereits seit 12 Jahren wegen einer Osteoporose mit multiplen Frakturen in Behandlung stand. Zum Zeitpunkt der Diagnose bestand eine schnell progrediente Myelom-niere sowie eine ausgedehnte tumor\u00f6se Raumforderung im Beckenbe-reich. Die Polychemotherapie nach dem VMCP-Schema f\u00fchrte zu einer Remission. Unsere differentialdiagnostischen Erw\u00e4gungen lassen uns die langj\u00e4hrige Osteoporose im vorliegenden Fall am ehesten als au\u00dfergew\u00f6hnlich langfristiges, monosymptomatisches Vorstadium eines multiplen Myeloms und weniger als unabh\u00e4ngige Ersterkrankung interpretieren.<\/jats:p>","DOI":"10.1159\/000215428","type":"journal-article","created":{"date-parts":[[2009,4,22]],"date-time":"2009-04-22T10:40:22Z","timestamp":1240396822000},"page":"152-155","source":"Crossref","is-referenced-by-count":0,"title":["Langj\u00e4hrige Osteoporose mit multiplen Frakturen als monosymptomatisches Fr\u00fchstadium eines multiplen Myeloms"],"prefix":"10.1159","author":[{"given":"K.","family":"Abbrederis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gattringer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Gastl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,21]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/215428","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000215428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:55:32Z","timestamp":1777679732000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000215428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,21]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000215428","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,21]]}}}