{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:58:13Z","timestamp":1777946293973,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,23]],"date-time":"2009-04-23T00:00:00Z","timestamp":1240444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,23]],"date-time":"2009-04-23T00:00:00Z","timestamp":1240444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemostasis"],"abstract":"<jats:p>A modified capillary thrombometer was constructed to study the rate of thrombus formation using heparinized whole blood (2 U\/ml) obtained from normal adults (n = 22) and children (n = 20) and patients with hemophilia A (n = 10) or von Willebrand\u2019s disease (n = 8). The median thrombosis times were as follows: normal adults =12.8 min (range = 4.5\u201326.0), normal children = 13.3 min (range = 5.7\u201329.0), patients with hemophilia A = 37.2 min (range = 20.0\u201360.0 min), and patients with von Willebrand\u2019s disease = 60.0 min (range = 37.2\u201360.0). Significant differences were demonstrated between all groups of subjects, except between normal adults and children. The capillary thrombometer appears to measure thrombus formation dependent on adequate Willebrand factor and platelets.<\/jats:p>","DOI":"10.1159\/000215555","type":"journal-article","created":{"date-parts":[[2009,4,23]],"date-time":"2009-04-23T08:05:14Z","timestamp":1240473914000},"page":"25-31","source":"Crossref","is-referenced-by-count":0,"title":["The Capillary Thrombometer Revisited"],"prefix":"10.1159","author":[{"given":"R.P.","family":"Kadota","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.J.W.","family":"Bowie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.C.","family":"Emslander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.N.","family":"Fass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.M.","family":"Ilstrup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,23]]},"container-title":["Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/215555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000215555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T16:35:40Z","timestamp":1777739740000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000215555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000215555","archive":["Portico"],"relation":{},"ISSN":["0301-0147","1423-0038"],"issn-type":[{"value":"0301-0147","type":"print"},{"value":"1423-0038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,23]]}}}