{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:25:45Z","timestamp":1777929945834,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T00:00:00Z","timestamp":1240531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T00:00:00Z","timestamp":1240531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Beim fortgeschrittenen Ovarialkarzinom ist mit hohen Rezidivraten und schlechten Therapieergebnissen f\u00fcr eine sekund\u00e4re Chemotherapie wie auch f\u00fcr Operation und Strahlentherapie zu rechnen. Im Vordergrund des therapeutischen Bem\u00fchens m\u00fcssen supportive Ma\u00dfnahmen stehen. Dar\u00fcber hinaus k\u00f6nnen intraperitoneale Therapieformen (Radioisotope oder Zytostatika) erprobt werden. Darmobstruktionen treten bei rund 35 % aller Patientinnen auf. Eine erfolgreiche Operation f\u00fchrt zur Verl\u00e4ngerung der \u00dcberlebenszeit.<\/jats:p>","DOI":"10.1159\/000215697","type":"journal-article","created":{"date-parts":[[2009,4,24]],"date-time":"2009-04-24T09:41:27Z","timestamp":1240566087000},"page":"403-409","source":"Crossref","is-referenced-by-count":1,"title":["Allgemeinbetreuung und operative Therapie bei progredientem oder rezidivierendem Ovarialkarzinom"],"prefix":"10.1159","author":[{"given":"M.","family":"Kaufmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,24]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/215697","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000215697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:58:41Z","timestamp":1777679921000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000215697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,24]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000215697","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,24]]}}}