{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:27:54Z","timestamp":1777930074194,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T00:00:00Z","timestamp":1240790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T00:00:00Z","timestamp":1240790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Die Fernmetastasierung der Struma maligna wurde anhand von 892 Schilddr\u00fcsenneoplasmen mit 151 M&lt;sub&gt;r&lt;\/sub&gt;F\u00e4llen untersucht. Die besondere Fragestellung gait dem Auftreten von Solit\u00e4rmetastasen und somit der Bedeutung einer kurativen Metastasenchirurgie. Die Aufschl\u00fcsselung nach histologischem Tumortyp zeigte deutliche Unterschiede: die hochdifferenzierten Karzinome tendieren eindeutig zur Metastasierung in den Knochen (35 von 54 M&lt;sub&gt;1&lt;\/sub&gt;-F\u00e4llen = 64,8%), wo wiederholt solit\u00e4re Herde vorzufinden waren (10 F\u00e4lle). An zweiter Stelle lag die Lunge mit einer stets multiplen Metastasierungsform (55,5%). Die anaplastischen Karzinome und Sarkome siedelten sich am h\u00e4ufigsten (70 von 81 M&lt;sub&gt;1&lt;\/sub&gt;-F\u00e4llen = 86%) in der Lunge \u2013 in 4 Fallen als Solit\u00e4rmetastasen \u2013 ab, deutlich seltener im Knochen (17,3%) und da meist multipel. In den \u00fcbrigen Organen traten vereinzelt bei alien histologischen Tumortypen Solit\u00e4rmetastasen auf.<\/jats:p>","DOI":"10.1159\/000216442","type":"journal-article","created":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T08:49:09Z","timestamp":1240822149000},"page":"350-355","source":"Crossref","is-referenced-by-count":1,"title":["Die Fernmetastasierung der Struma maligna"],"prefix":"10.1159","author":[{"given":"M.","family":"Hermann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Kober","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Keminger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,27]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/216442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000216442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:02:34Z","timestamp":1777680154000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000216442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000216442","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,27]]}}}