{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:28:07Z","timestamp":1777930087781,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T00:00:00Z","timestamp":1240790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T00:00:00Z","timestamp":1240790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Onkologie"],"abstract":"<jats:p>Hypophysenmetastasen sind selten. Angaben \u00fcber die Inzidenz in Autopsieserien schwanken zwischen 1,8 und 12% der metastasieren-den Tumoren. Die meisten finden sich beim Mammakarzinom, gefolgt von Karzinomen des Magen-Darm-Traktes. Klinisch werden nur 20% manifest in Form eines Diabetes insipidus \u2013 entsprechend dem bevorzugten Befall des Hypophysenhinterlappens. Es werden die Besonderheiten eines Falles von Prostatakarzinom mit Hypophysenmetastase diskutiert, bei dem eine Funktionsst\u00f6rung der parasell\u00e4r verlaufenden Hirnnerven zur Diagnose f\u00fchrte. Die Behandlung mit Flutamid erbrachte eine Remission. Die \u00dcberlebenszeit war mit 18 Monaten lang.<\/jats:p>","DOI":"10.1159\/000216489","type":"journal-article","created":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T08:49:09Z","timestamp":1240822149000},"page":"66-69","source":"Crossref","is-referenced-by-count":2,"title":["Klinik der hypophys\u00e4ren Metastasierungen"],"prefix":"10.1159","author":[{"given":"U.","family":"Szuwart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.-J.","family":"K\u00f6nig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Bennefeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ch.","family":"Weritz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kleinhans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,4,27]]},"container-title":["Onkologie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/216489","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000216489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:03:16Z","timestamp":1777680196000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000216489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000216489","archive":["Portico"],"relation":{},"ISSN":["0378-584X","1423-0240"],"issn-type":[{"value":"0378-584X","type":"print"},{"value":"1423-0240","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,27]]}}}