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Karger AG","issue":"4","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychopathology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>There is general agreement that DSM-IV and ICD-10 require major improvements in format and content to make them more valid, evidence-based and clinically useful. DSM-IV-TR currently includes a series of clinical features that provide potentially useful information on cross-sectional and longitudinal courses of bipolar disorder. This conceptual and data-driven review proposes changes in the current classification by removing, modifying and adding bipolar episode and course specifiers in DSM-V. Specifiers to be maintained would be \u2018with catatonic features\u2019, \u2018with melancholic features\u2019, \u2018with atypical features\u2019 and \u2018with rapid cycling\u2019. The \u2018seasonal pattern\u2019 modifier should be amended to allow manic, hypomanic and mixed episodes to be included in the description. Some specifiers should likely be substantially reconceptualized (\u2018severity\/psychosis\/remission\u2019) or removed (\u2018with post-partum onset\u2019). Age at onset (early, intermediate or late onset) and predominant polarity (manic, depressive) should be added for their relevance for course and outcome.<\/jats:p>","DOI":"10.1159\/000218518","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T17:58:18Z","timestamp":1242410298000},"page":"209-218","source":"Crossref","is-referenced-by-count":58,"title":["The Road to 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