{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:19:24Z","timestamp":1761823164405,"version":"3.40.4"},"reference-count":10,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Intracranial intra-arterial calcifications (ICAC) are a common finding on head CT examinations, but their significance is not known. The aim of this study is to determine if a relationship exists between ICAC on head CT and the presence of a high-grade atherosclerotic stenosis on cerebral angiography. &lt;i&gt;Methods:&lt;\/i&gt; This was a retrospective study of 108 consecutive patients admitted to the stroke service at Parkland Hospital in Dallas, Tex., USA. Each patient had undergone a head CT and catheter-based angiographic study to meet the inclusion criteria. Demographic information was recorded along with CT imaging data in regards to the amount of calcification. Angiographic images were reviewed independently, and a comparison was made to determine if calcification was predictive of finding a high-grade stenosis on angiography. &lt;i&gt;Results:&lt;\/i&gt; A total of 108 consecutive patients with a mean age of 56 \u00b1 12 years were studied. Of the 540 vessels studied, 65 (12%) were found to have a stenosis of \u226550% on angiography, and 71 (13.1%) were found to have a calcium grade of 3 or 4 on head CT. ICAC appeared to be more common in the anterior circulation compared to the posterior circulation. Patients with grade 3 or 4 calcification of an intracranial vessel on head CT were more likely to have a stenosis of \u226550% on cerebral angiography.&lt;i&gt; Conclusions:&lt;\/i&gt; The presence of ICAC on head CT appears to correlate with the presence of an underlying intracranial stenosis on angiography. Further study is required to validate these preliminary findings.<\/jats:p>","DOI":"10.1159\/000219296","type":"journal-article","created":{"date-parts":[[2009,5,20]],"date-time":"2009-05-20T12:26:46Z","timestamp":1242822406000},"page":"45-48","source":"Crossref","is-referenced-by-count":32,"title":["Extent of Intra-Arterial Calcification on Head CT Is Predictive of the Degree of Intracranial Atherosclerosis on Digital Subtraction Angiography"],"prefix":"10.1159","volume":"28","author":[{"given":"Mounzer Y.","family":"Kassab","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishi","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arshad","family":"Majid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad U.","family":"Farooq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian P.","family":"Giles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dion F.","family":"Graybeal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Rappard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,5,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2864%2991625-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00301683"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jacc.2005.05.049"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.atherosclerosis.2005.10.010"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs0202.103071"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000090206"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000080772"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2292021016"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2441051769"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2212001612"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/219296","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/219296","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:33:49Z","timestamp":1745447629000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000219296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2009,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000219296","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2009]]}}}