{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T23:43:45Z","timestamp":1777765425592,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,5,25]],"date-time":"2009-05-25T00:00:00Z","timestamp":1243209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,5,25]],"date-time":"2009-05-25T00:00:00Z","timestamp":1243209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"abstract":"<jats:p>14 patients with lower respiratory tract infections, 6 with postoperative Staphylococcus aureus infections, 5 with erysipelas, 4 with septicemia, and 1 with Diplococcus pneumoniae meningitis were treated with 1 g cephalexin parenterally 4\u20136 times daily. 27 patients were cured and 1 improved; 1 patient with myco-plasma pneumonia and the meningitis patient failed to respond to therapy. In contrast to intravenous injection, intramuscular administration resulted in low peak levels and prolonged elimination of the drug. 7 patients who received intramuscular therapy complained of pain at the site of injection, and 2 patients became dyspneic during intravenous injections. Parenteral administration of cephalexin may be useful in the treatment of septicemia, lower respiratory tract and soft tissue infections. However, further evaluation of side effects seems advisable.<\/jats:p>","DOI":"10.1159\/000221458","type":"journal-article","created":{"date-parts":[[2009,5,25]],"date-time":"2009-05-25T11:08:22Z","timestamp":1243249702000},"page":"215-220","source":"Crossref","is-referenced-by-count":4,"title":["Therapy of Infections with Parenteral Cephalexin"],"prefix":"10.1159","author":[{"given":"C.O.","family":"Solberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schreiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Hamre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Digranes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,5,25]]},"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000221458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:23:28Z","timestamp":1777476208000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000221458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,25]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000221458","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,25]]}}}