{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:47:15Z","timestamp":1745470035862,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transfus Med Hemother"],"published-print":{"date-parts":[[1984]]},"abstract":"<jats:p>Cryoprecipitates (CP) and cryodepleted plasma (CDP) were prepared from fresh frozen plasma (FFP). Plasma was easily and cleanly frozen at -50\u00b0 C using a methanolbath Ultracryostat, which has been available commercially for the past few years. From a random sample (n = 6), factors VIIl\u00b7C, IX:C, V:C, fibrinogen, antithrombin III and fibronectin were determined. Concerning the total contents and the in-vitro-recovery of factor VIIL\u00b7C (x:104 IU\/53.5%) and fibrinogen x:175mg\/36.9%), the preparation method was as efficient as other equally common methods. Apart from the well-known applications, CP may be used for the substitution of fibronectin (x:46.2mg\/73.0%). The supernatant plasma of cryoprecipitation (CDP) can be utilized for substitution of coagulation disorders especially deficiencies of the prothrombincomplex and antithrombin III (x:IX:C:183 IU\/76.2%; V:C:140.5 U\/73.8%; AT Ill:162 U\/80.2%).<\/jats:p>","DOI":"10.1159\/000221691","type":"journal-article","created":{"date-parts":[[2009,5,25]],"date-time":"2009-05-25T15:08:22Z","timestamp":1243264102000},"page":"342-344","source":"Crossref","is-referenced-by-count":1,"title":["Simple Method for Preparation of Cryoprecipitate (CP) and Cryodepleted Plasma (CDP)"],"prefix":"10.1159","volume":"11","author":[{"given":"W.","family":"Prohaska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Kretschmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,5,22]]},"container-title":["Transfusion Medicine and Hemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/221691","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/221691","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:49:18Z","timestamp":1745448558000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000221691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984]]},"references-count":0,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2004,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000221691","archive":["Portico"],"relation":{},"ISSN":["1660-3796","1660-3818"],"issn-type":[{"type":"print","value":"1660-3796"},{"type":"electronic","value":"1660-3818"}],"subject":[],"published":{"date-parts":[[1984]]}}}