{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T23:10:49Z","timestamp":1790550649724,"version":"4.1.0"},"reference-count":19,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2009]]},"abstract":"<i>Background:<\/i> Chronic endometritis (CE) is a subtle pathology causing infertility and abnormal uterine bleeding. We evaluated the reliability of vaginal and cervical cultures for detecting infectious agents at the endometrial level. <i>Methods:<\/i> In a prospective diagnostic study, 181 women diagnosed with CE and 100 controls underwent vaginal, endocervical and endometrial sampling. Cultures for common bacteria<i>, Neisseria gonorrhoeae, <\/i>yeast and <i>Ureaplasma urealyticum<\/i> and PCR for <i>Chlamydia trachomatis<\/i> were performed. <i>Results:<\/i> The prevalent infectious agents at the endometrial level were common bacteria(59.7% of cases); <i>U. urealyticum<\/i> was detected in 11.0% and <i>C. trachomatis<\/i> in only 2.8%. The concordance rate between endocervical and endometrial specimens for common bacteria was 48.3%; 100% for <i>C. trachomatis<\/i> and 58.3% for <i>U. urealyticum. <\/i>The concordance rate between vaginal and endometrial cultures for common bacteria was 50.2%, only 16.7% for <i>C. trachomatis<\/i> and 48.8% for <i>U. urealyticum.<\/i> For common bacteria both vaginal and cervical cultures showed low sensitivities of 0.30 and 0.19, respectively. <i>Conclusion:<\/i> Common bacteria and <i>U. urealyticum <\/i>were the prevalent infectious agents in the uterine cavity of women diagnosed with CE. Both vaginal and endocervical cultures had low concordance with endometrial cultures. Only <i>C. trachomatis<\/i> test at cervical level had high concordance with endometrial findings.<\/jats:p>","DOI":"10.1159\/000223819","type":"journal-article","created":{"date-parts":[[2009,6,10]],"date-time":"2009-06-10T17:42:04Z","timestamp":1244655724000},"page":"108-115","source":"Crossref","is-referenced-by-count":119,"title":["Poor Reliability of Vaginal and Endocervical Cultures for Evaluating Microbiology of Endometrial Cavity in Women with Chronic Endometritis"],"prefix":"10.1159","volume":"68","author":[{"given":"Ettore","family":"Cicinelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"De Ziegler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Tinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Saliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Resta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Bellavia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danila","family":"De Vito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,6,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00000478-199002000-00008"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS1297-9589%2803%2900007-9"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00003081-198809000-00006"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2000.106180"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2005.11.050"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000072075"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136%2Fjcp.38.7.726"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jmig.2005.07.394"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumrep%2Fdeh779"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2002.121625"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2F0029-7844%2894%2900400-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1155%2FS1064744903000024"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093%2Fhumrep%2F17.2.337"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.fertnstert.2004.01.054"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2006.04.010"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS0046-8177%2896%2990288-9"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007%2Fs11908-005-0049-2"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jmig.2005.06.004"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1086%2F425929"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/223819","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/223819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:36:54Z","timestamp":1745447814000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000223819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":19,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2009,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000223819","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}