{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:59:48Z","timestamp":1777928388998,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T00:00:00Z","timestamp":1244505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,6,9]],"date-time":"2009-06-09T00:00:00Z","timestamp":1244505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncology"],"abstract":"<jats:p>The analysis of 73 cases revealed Paget\u2019s disease of the nipple, known as a precancerous state, to be a special form of the intraductal mammary cancers. In the majority of the cases, apart from a superficial exulceration malignant transformation in the glandular substance is present. Thus, the treatment schedules have to be similar to those of other mammary cancers; in cases localized to the nipple, simple mastectomy with axillary block dissection, is suggested; in cases with tumors of the glandular substance, radical mastectomy according to Halsted is suggested. The frequent negligency is partly a result of an earlier attitude of the physicians being too conservative with therapeutic procedures.<\/jats:p>","DOI":"10.1159\/000224967","type":"journal-article","created":{"date-parts":[[2009,6,10]],"date-time":"2009-06-10T13:42:04Z","timestamp":1244641324000},"page":"278-293","source":"Crossref","is-referenced-by-count":7,"title":["Characteristics of Paget\u2019s Carcinoma of the Nipple and Problems of its Negligency"],"prefix":"10.1159","author":[{"given":"G.","family":"Mal\u00e1k","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Tapolcs\u00e1nyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,6,9]]},"container-title":["Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/224967","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000224967","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:11:56Z","timestamp":1777677116000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000224967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,9]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000224967","archive":["Portico"],"relation":{},"ISSN":["0030-2414","1423-0232"],"issn-type":[{"value":"0030-2414","type":"print"},{"value":"1423-0232","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,9]]}}}