{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:56:59Z","timestamp":1791928619796,"version":"4.3.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Purpose:&lt;\/i&gt; Alagille syndrome is frequently associated with optic disc anomalies. This is the first report of a patient with Alagille syndrome and myelinated retinal nerve fibers. &lt;i&gt;Methods:&lt;\/i&gt; A 5-year-old female patient was referred to the Centre for Ophthalmology before a liver transplantation. Ocular examinations including slit lamp examination and funduscopy as well as anterior segment and fundus images were performed. &lt;i&gt;Results:&lt;\/i&gt; We observed myelinated retinal nerve fibers in both eyes of a 5-year-old female patient with Alagille syndrome. &lt;i&gt;Conclusions:&lt;\/i&gt; A broad spectrum of ocular anomalies is associated with Alagille syndrome. To our knowledge, this is the first reported case of myelinated retinal nerve fibers in a patient with Alagille syndrome.<\/jats:p>","DOI":"10.1159\/000226259","type":"journal-article","created":{"date-parts":[[2009,7,6]],"date-time":"2009-07-06T10:41:43Z","timestamp":1246876903000},"page":"348-350","source":"Crossref","is-referenced-by-count":8,"title":["Alagille Syndrome Associated with Myelinated Retinal Nerve Fibers"],"prefix":"10.1159","volume":"223","author":[{"given":"Bogomil","family":"Voykov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuella","family":"Guenova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekkehard","family":"Sturm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Deuter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,7,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fhumu.20310"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1086%2F505332"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136%2Fjmg.32.4.264"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038%2Fng0797-243"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0161-6420%2899%2990072-6"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0181-5512%2808%2970333-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00417-006-0340-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000310082"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/226259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/226259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:03:12Z","timestamp":1745449392000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000226259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2009,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000226259","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}