{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:01:37Z","timestamp":1792544497771,"version":"4.5.0"},"reference-count":30,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Antibiotics are frequently used to treat hidradenitis suppurativa (HS); however, few data on their efficacy are available. &lt;i&gt;Objective:&lt;\/i&gt; To evaluate the efficacy of a combination of systemic clindamycin (300 mg twice daily) and rifampicin (600 mg daily) in the treatment of patients with severe HS. &lt;i&gt;Methods:&lt;\/i&gt; Patients (n = 116) who received this combination were studied retrospectively. The main outcome measure was the severity of the disease, assessed by the Sartorius score, before and after 10 weeks of treatment. &lt;i&gt;Results:&lt;\/i&gt; The Sartorius score dramatically improved at the end of treatment (median = 29, interquartile range = 14.5, vs. median = 14.5, interquartile range = 11; p &lt; 0.001), as did other parameters of severity as well as the quality of life score. Eight patients (6.9%) stopped the treatment because of side effects. &lt;i&gt;Conclusion:&lt;\/i&gt; The combination of clindamycin and rifampicin is effective in the treatment of severe HS.<\/jats:p>","DOI":"10.1159\/000228334","type":"journal-article","created":{"date-parts":[[2009,7,7]],"date-time":"2009-07-07T10:38:56Z","timestamp":1246963136000},"page":"148-154","source":"Crossref","is-referenced-by-count":220,"title":["Combination Therapy with Clindamycin and Rifampicin for Hidradenitis Suppurativa: A Series of 116 Consecutive 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