{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:36:37Z","timestamp":1779910597290,"version":"3.53.1"},"reference-count":8,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>The &lt;i&gt;Bartonella&lt;\/i&gt; species have been recently recognized as important causative agents of culture-negative bacterial endocarditis. Antineutrophil cytoplasmic antibodies (ANCAs) have been associated with the spectrum of idiopathic small vessel vasculitis. However, a variety of infections can result in a false-positive ANCA test, and especially subacute bacterial endocarditis (SBE) with the presence of ANCAs occasionally mimics the clinical manifestations of an ANCA-associated vasculitis such as skin purpura and glomerulonephritis. In contrast, noninfectious endocardial involvement is known to be part of the spectrum of the manifestations of the ANCA-associated vasculitis. Therefore, it is crucial to distinguish an ANCA-positive SBE from an ANCA-associated vasculitis with endocardial compromise, because the misdiagnosis of an SBE as an ANCA-associated vasculitis can lead to an inappropriate immunosuppressive therapy with catastrophic consequences. The differential diagnosis is sometimes difficult, especially in the case of culture-negative infective endocarditis with a positive ANCA test. We describe here a case of a culture-negative SBE caused by &lt;i&gt;Bartonella&lt;\/i&gt;&lt;i&gt;quintana,&lt;\/i&gt; accompanied with a positive cytoplasmic ANCA test and clinical findings masquerading as ANCA-associated vasculitis. Both a serological test for &lt;i&gt;Bartonella&lt;\/i&gt; and polymerase chain reaction restriction fragment length polymorphism analysis were helpful for a correct diagnosis and appropriate treatment.<\/jats:p>","DOI":"10.1159\/000228645","type":"journal-article","created":{"date-parts":[[2009,7,15]],"date-time":"2009-07-15T13:29:55Z","timestamp":1247664595000},"page":"208-211","source":"Crossref","is-referenced-by-count":39,"title":["Infective Endocarditis by &lt;i&gt;Bartonella&lt;\/i&gt;&lt;i&gt;quintana&lt;\/i&gt; Masquerading as Antineutrophil Cytoplasmic Antibody-Associated Small Vessel Vasculitis"],"prefix":"10.1159","volume":"114","author":[{"given":"Hiroaki","family":"Sugiyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Sahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koh","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryozo","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291096-9896%28200002%29190%3A3%3C349%3A%3AAID-PATH524%3E3.0.CO%3B2-A"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10067-005-0176-z"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00005792-200107000-00003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2FBF01708232"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128%2FJCM.42.8.3462-3468.2004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F1529-0131%28200001%2943%3A1%3C226%3A%3AAID-ANR27%3E3.0.CO%3B2-Q"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.159.15.1807"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0140-6736%2891%2991427-V"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/228645","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/228645","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T21:43:27Z","timestamp":1745444607000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000228645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":8,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,9,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000228645","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}