{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:00:20Z","timestamp":1777899620652,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,7,23]],"date-time":"2009-07-23T00:00:00Z","timestamp":1248307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,7,23]],"date-time":"2009-07-23T00:00:00Z","timestamp":1248307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Appl Imm"],"abstract":"<jats:p>Distribution of 51Cr-tagged lymphocytes between lymph nodes and other tissues in rats was studied after an intravenous injection of labeled isogenic cells. The proportion of radioactivity in the lymph nodes was reduced by the following measures: heating the cells at 65 \u00b0C for 15 min, incubating them in vitro with mechlorethamine (HN&lt;sub&gt;2&lt;\/sub&gt;) or mannomustine; pretreating the cell donor animals with cyclophosphamide 30 mg\/kg daily for 3 days. Incubating 51Cr-labeled cells with various bioeffective cyclophosphamide metabolites in vitro had remarkably little effect on their subsequent distribution in vivo in contrast to HN&lt;sub&gt;2&lt;\/sub&gt;. Continually infusing cyclophosphamide for 24 h or a single massive infusion of cortisol hemisuccinate into recipients of 51Cr cells did not alter cell homing to lymphoid tissues.<\/jats:p>","DOI":"10.1159\/000231121","type":"journal-article","created":{"date-parts":[[2009,7,28]],"date-time":"2009-07-28T02:24:43Z","timestamp":1248747883000},"page":"172-182","source":"Crossref","is-referenced-by-count":4,"title":["Effect of some Nitrogen Mustards and Thoracic Duct Drainage on Lymphocyte Distribution in Rats"],"prefix":"10.1159","author":[{"given":"David T.Y.","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Whitehouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,7,23]]},"container-title":["International Archives of Allergy and Applied Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/231121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000231121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:09:19Z","timestamp":1777630159000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000231121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,23]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000231121","archive":["Portico"],"relation":{},"ISSN":["0020-5915","2571-6662"],"issn-type":[{"value":"0020-5915","type":"print"},{"value":"2571-6662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,23]]}}}