{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:13:21Z","timestamp":1777900401392,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,7,30]],"date-time":"2009-07-30T00:00:00Z","timestamp":1248912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,7,30]],"date-time":"2009-07-30T00:00:00Z","timestamp":1248912000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Appl Imm"],"abstract":"<jats:p>Mononuclear cell suspension from synovial fluids of 13 patients with rheumatoid arthritis and 5 patients with juvenile rheumatoid arthritis contained an average of 1.5 and 1.3% cytotoxic plaque-forming cells, respectively, when tested against a monolayer of antibody-sensitized sheep erythrocytes. The plaque-forming ability was completely abolished after removal of cells which had phagocytosed carbonyl iron. The highest proportion of plaque-forming cells was found in the cell suspensions that contained the highest percentage of peroxidase-positive mononuclear cells. The plaque-forming activity was almost completely inhibited by human IgG. Cell suspensions from patients treated with corticosteroids contained the highest proportions of plaque-forming cells and peroxidase-positive mononuclear cells compared with patients not receiving such treatment. Our findings indicate that the plaque-forming leukocytes in rheumatoid synovial fluid are monocytes.<\/jats:p>","DOI":"10.1159\/000232674","type":"journal-article","created":{"date-parts":[[2009,7,31]],"date-time":"2009-07-31T07:27:44Z","timestamp":1249025264000},"page":"60-66","source":"Crossref","is-referenced-by-count":3,"title":["Identification and Functional Characterization of Monocytes in Rheumatoid Synovial Fluid"],"prefix":"10.1159","author":[{"given":"L.","family":"Thorsteinsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.G.","family":"Abrahamsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.S.","family":"Fr\u00f8land","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.E.","family":"K\u00e5ss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,7,30]]},"container-title":["International Archives of Allergy and Applied Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/232674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000232674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:28:50Z","timestamp":1777631330000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000232674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000232674","archive":["Portico"],"relation":{},"ISSN":["0020-5915","2571-6662"],"issn-type":[{"value":"0020-5915","type":"print"},{"value":"2571-6662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,30]]}}}