{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:22:20Z","timestamp":1777900940576,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,8,5]],"date-time":"2009-08-05T00:00:00Z","timestamp":1249430400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,8,5]],"date-time":"2009-08-05T00:00:00Z","timestamp":1249430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Appl Imm"],"abstract":"<jats:p>Since a protease inhibitor or anaphylatoxin inactivator deficiency might explain why certain individuals are prone to develop chronic urticaria\/angioedema or anaphylactoid reactions to radiographic contrast media, serum \u03b1j-protease inhibitor, \u03b1&lt;sub&gt;1&lt;\/sub&gt;-antichymotrypsin, \u03b1&lt;sub&gt;2&lt;\/sub&gt;-macroglobulin, inter-\u03b1-inhibitor, anti-thrombin III, \u03b1&lt;sub&gt;2&lt;\/sub&gt;-plasmin inhibitor, C1 inhibitor, and serum carboxypeptidase N were assessed by immunologic or functional methods. These values all were within normal limits in both groups of patients except for a low mean \u03b1&lt;sub&gt;1&lt;\/sub&gt;-protease inhibitor level in chronic idiopathic urticaria\/angioedema and cold urticaria patients and marginal decreases of \u03b1&lt;sub&gt;1&lt;\/sub&gt;-protease and inter-\u03b1-inhibitor levels in radiographic contrast medium reactors. However, these abnormalities were not thought to be of pathogenetic significance.<\/jats:p>","DOI":"10.1159\/000233975","type":"journal-article","created":{"date-parts":[[2009,8,5]],"date-time":"2009-08-05T05:41:56Z","timestamp":1249450916000},"page":"220-223","source":"Crossref","is-referenced-by-count":6,"title":["Plasma Protease Inhibitor and Anaphylatoxin Inactivator Levels in Chronic Urticaria\/Angioedema and in Patients Experiencing Anaphylactoid Reactions to Radiographic Contrast Media"],"prefix":"10.1159","author":[{"given":"Kenneth P.","family":"Mathews","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline M.","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A.","family":"Amendola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred.H.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,8,5]]},"container-title":["International Archives of Allergy and Applied Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/233975","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000233975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:46:32Z","timestamp":1777632392000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000233975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,5]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000233975","archive":["Portico"],"relation":{},"ISSN":["0020-5915","2571-6662"],"issn-type":[{"value":"0020-5915","type":"print"},{"value":"2571-6662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,5]]}}}