{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:52:07Z","timestamp":1790664727373,"version":"4.1.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,8,7]],"date-time":"2009-08-07T00:00:00Z","timestamp":1249603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,8,7]],"date-time":"2009-08-07T00:00:00Z","timestamp":1249603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Appl Imm"],"abstract":"<jats:p>Most of the IgE response in persons allergic to cats is directed against the cat allergen Fe1 d I (Felis domesticus allergen I). Although the presence of Fe1 d I in saliva has been demonstrated, the source of Fe1 d I is not completely known. We measured Fe1 d I concentrations in the cat\u2019s lacrimal and salivary glands and in the excretes lacrimal fluid, milk and saliva. The concentration of Fe1 d I, determined by a radioimmunoassay, in the lacrimal gland was 390\u2013780 mU\/g tissue and in the sublingual gland 610 mU\/g tissue. In the parotid gland and especially the submandibular gland only low concentrations were found, respectively 70\u2013210 and 40\u201350 mU\/g tissue. In lacrimal fluid 6.8\u201314 U\/ml Fe1 d l was detected, which is comparable to saliva, 4.2\u20137.0 U\/ml, whereas in cat\u2019s milk only 0.33 U\/ml Fel d I was found. Immunohistochemical studies with monoclonal antibody directed against Fe1 d I (anti-Fe1 d I) showed the presence of Fe1 d I in the serous cells of the lacrimal gland. Thus, our results demonstrate that in particular the lacrimal gland might be a useful Fe1 d I source.<\/jats:p>","DOI":"10.1159\/000235168","type":"journal-article","created":{"date-parts":[[2009,8,7]],"date-time":"2009-08-07T09:46:18Z","timestamp":1249638378000},"page":"375-378","source":"Crossref","is-referenced-by-count":31,"title":["Presence of Felis domesticus Allergen I in the Cat\u2019s Salivary and Lacrimal Glands"],"prefix":"10.1159","author":[{"given":"Florine J.","family":"van Milligen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thea M.","family":"Vroom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob C.","family":"Aalberse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,8,7]]},"container-title":["International Archives of Allergy and Applied Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/235168","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000235168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:05:48Z","timestamp":1777633548000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000235168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000235168","archive":["Portico"],"relation":{},"ISSN":["0020-5915","2571-6662"],"issn-type":[{"value":"0020-5915","type":"print"},{"value":"2571-6662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,7]]}}}