{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:02:23Z","timestamp":1791975743512,"version":"4.4.0"},"reference-count":19,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Anti-tumor-necrosis-factor-\u03b1 agents are limited by their side effects. Eczema is one of the most frequent adverse reactions affecting quality of life. &lt;i&gt;Objective:&lt;\/i&gt; To assess potential predictive risk factors for eczema in patients receiving infliximab. &lt;i&gt;Methods:&lt;\/i&gt; We conducted a prospective cohort study including patients treated with infliximab for a variety of disorders with the exception of cutaneous psoriasis. Clinical features were compared among patients with and without eczema under therapy. &lt;i&gt;Results:&lt;\/i&gt; 92 consecutive patients were included; 15 developed eczema after the initiation of infliximab. In univariate analyses, a personal history of atopic symptoms was the only predictive factor for the occurrence of eczema (odds ratio = 3.6). Sex, age, principal diagnosis, dose and duration of infliximab and concomitant use of other immunosuppressors had no influence on the occurrence of eczema. &lt;i&gt;Conclusions:&lt;\/i&gt; A personal history of atopic symptoms is predictive of eczema under infliximab. Specific information should be provided to atopic patients starting such a treatment.<\/jats:p>","DOI":"10.1159\/000235582","type":"journal-article","created":{"date-parts":[[2009,8,12]],"date-time":"2009-08-12T13:50:19Z","timestamp":1250085019000},"page":"263-267","source":"Crossref","is-referenced-by-count":44,"title":["Predictive Factors of Eczema-Like Eruptions among Patients without Cutaneous Psoriasis Receiving Infliximab: A Cohort Study of 92 Patients"],"prefix":"10.1159","volume":"219","author":[{"given":"Abdolrasool","family":"Esmailzadeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Yousefi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Farhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Bachmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Cosnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Berenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Duriez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Aractingi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiarash","family":"Khosrotehrani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,8,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.pharmthera.2007.10.001"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa011110"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.295.19.2275"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2007.07682.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000069965"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1067%2FS0190-9622%2803%2902107-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186%2Far1724"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2000.03417.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1183%2F09031936.95.08030483"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2008.08514.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2F01.all.0000182538.63273.a3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136%2Fard.2007.087288"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0151-9638%2807%2989187-3"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1468-3083.2008.02935.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093%2Frheumatology%2F39.9.1020"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Fard.61.11.968"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.140.2.215"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2008.08436.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaci.2007.10.028"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/235582","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/235582","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:07:47Z","timestamp":1745446067000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000235582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000235582","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}