{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:25Z","timestamp":1787017885351,"version":"build-2736575974"},"reference-count":11,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke\u2019s encephalopathy with cortical abnormalities (WEc). &lt;i&gt;Methods:&lt;\/i&gt; We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. &lt;i&gt;Results:&lt;\/i&gt; Besides the classical triad of ocular abnormalities, ataxia and global confusion, muscular weakness of all extremities was frequently recognized (5 of 6 evaluable cases; 83%). During the clinical courses, 2 patients (20%) died and 1 fell into a vegetative state. The cortical abnormalities were distributed in the frontal and parietal lobes, especially around the bilateral central sulcus, in all cases. In 1 case, the cortical abnormality was irreversible, and the abnormal lesion, similar to that seen in laminar necrosis, persisted. &lt;i&gt;Conclusions:&lt;\/i&gt; Bilateral frontal cortical abnormalities around the central sulcus and muscular weakness of all extremities might be the characteristic features of WEc.<\/jats:p>","DOI":"10.1159\/000235596","type":"journal-article","created":{"date-parts":[[2009,8,19]],"date-time":"2009-08-19T10:21:35Z","timestamp":1250677295000},"page":"274-280","source":"Crossref","is-referenced-by-count":17,"title":["Wernicke\u2019s Encephalopathy with Cortical Abnormalities: Clinicoradiological Features: Report of 3 New Cases and Review of the Literature"],"prefix":"10.1159","volume":"62","author":[{"given":"Keita","family":"Sakurai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Hara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takemori","family":"Yamawaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Shibamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,8,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00004728-199503000-00026"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002340000393"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.clineuro.2005.05.010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2F00004728-200303000-00022"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00234-003-1043-8"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.49.4.341"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3174%2Fajnr.A0827"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1471-4159.2001.00436.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1471-4159.1993.tb03635.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.pbb.2006.03.004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1530-0277.1996.tb01106.x"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/235596","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/235596","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:07:53Z","timestamp":1745431673000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000235596"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":11,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2009,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000235596","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}