{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:45:46Z","timestamp":1745469946870,"version":"3.40.4"},"reference-count":7,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; We evaluated the safety and efficacy of CO&lt;sub&gt;2&lt;\/sub&gt; laser conization in pregnant women with cervical intraepithelial neoplasia 3\/carcinoma in situ (CIN3\/CIS) or microinvasive carcinoma (MIC). &lt;i&gt;Objectives:&lt;\/i&gt; A total of 49 pregnant women with biopsy-proven CIN3\/CIS (30 patients) or MIC (19 patients) were studied.&lt;i&gt;Methods:&lt;\/i&gt; Retrospective analysis based on clinical records. &lt;i&gt;Results:&lt;\/i&gt; Median age and median week of gestation were 31 years (range: 22\u201339) and 17 weeks (range: 7\u201333), respectively. The median length of cervix resected by conization, median duration of surgery and median blood loss were 14 mm (range: 5\u201323), 20 min (range: 7\u201335) and 78 ml (range: 10\u2013797), respectively. One biopsy-proven CIN3\/CIS patient was diagnosed with Federation of Gynecology and Obstetrics (FIGO) Ia2 and 3 biopsy-proven MIC patients were diagnosed with FIGO Ib1 based on conization specimens. A total of 35 patients could be followed until delivery, of which 27 (77.1%) patients delivered transvaginally. Although 8 patients (22.9%) had a cesarean section and 6 patients (17.1%) delivered preterm, no conization-related obstetric complications were observed. &lt;i&gt;Conclusion:&lt;\/i&gt; Since it results in few obstetric complications, CO&lt;sub&gt;2&lt;\/sub&gt; laser conization within 20 mm of length can be considered a safe procedure for pregnant women.<\/jats:p>","DOI":"10.1159\/000236366","type":"journal-article","created":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T13:21:59Z","timestamp":1252502519000},"page":"230-233","source":"Crossref","is-referenced-by-count":8,"title":["Retrospective Evaluation of CO&lt;sub&gt;2&lt;\/sub&gt; Laser Conization in Pregnant Women with Carcinoma in situ or Microinvasive Carcinoma"],"prefix":"10.1159","volume":"68","author":[{"given":"Mitsuhiro","family":"Tsuritani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoh","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Kotani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taeko","family":"Kataoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hoshiai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00004347-199501000-00011"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00404-005-0032-z"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2008.04.010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2007.12.011"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2007.07.050"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1525-1438.2007.00802.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ygyno.2008.01.016"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/236366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/236366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:15:30Z","timestamp":1745446530000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000236366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2009,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000236366","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"type":"print","value":"0378-7346"},{"type":"electronic","value":"1423-002X"}],"subject":[],"published":{"date-parts":[[2009]]}}}