{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T23:53:20Z","timestamp":1777766000904,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,8]],"date-time":"2009-09-08T00:00:00Z","timestamp":1252368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,8]],"date-time":"2009-09-08T00:00:00Z","timestamp":1252368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"abstract":"<jats:p>Chloramphenicol and thiamphenicol were tested by the agar dilution method against 105 Salmonella typhi, 15 S. paratyphi A, 6 S. paratyphi B, 8 S. paratyphi C, 57 Haemophilus influenzae and 60 Neisseriagonorrhoeae strains. The two drugs showed similar in vitro activity against strains of H. influenzae and N. gonorrhoeae irrespective of their \u03b2-lactamase production. In contrast, while all the tested isolatels of typhoid and paratyphoid fever Salmonella were susceptible to chloramphenicol, most of these strains showed resistance to thiamphenicol with MICs &gt; 8 \u00b5g\/ml. The significance of these findings are discussed.<\/jats:p>","DOI":"10.1159\/000238064","type":"journal-article","created":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T09:21:59Z","timestamp":1252488119000},"page":"105-109","source":"Crossref","is-referenced-by-count":1,"title":["Comparative in vitro Activity of Chloramphenicol and Thiamphenicol against Haemophilus Influenzae, Neisseria Gonorrhoeae and the Typhoid and Paratyphoid Bacilli"],"prefix":"10.1159","author":[{"given":"W.S.","family":"Ng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.Y.","family":"Chau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,8]]},"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/238064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000238064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:30:59Z","timestamp":1777476659000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000238064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000238064","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,8]]}}}