{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T23:56:51Z","timestamp":1777766211668,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,8]],"date-time":"2009-09-08T00:00:00Z","timestamp":1252368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,8]],"date-time":"2009-09-08T00:00:00Z","timestamp":1252368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"abstract":"<jats:p>We examined 160 strains of Enterobacteriaceae and Pseudomonas aeruginosa for susceptibility to cefoxitin, aminoglycosides, and other \u03b2-lactam antibiotics, alone and in combination. The aminoglycosides were the most effective agents tested, but, except for some strains, cefoxitin inhibited all organisms at a 90% minimal inhibitory concentration of 25 \u03bcg or less per ml. We observed a relatively high incidence of antagonism or nonsynergy when cefoxitin was tested in combination with other agents against 33 gentamicin-susceptible gram-negative bacilli. No synergy was observed when various combinations with cefoxitin were tested against three strains of cephalothin-resistant, carbenicillin-resistant Enterobacteriaceae of varying gentamicin susceptibility.<\/jats:p>","DOI":"10.1159\/000238180","type":"journal-article","created":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T09:21:59Z","timestamp":1252488119000},"page":"89-98","source":"Crossref","is-referenced-by-count":4,"title":["In vitro Activity of Cefoxitin, Alone and in Combination with Aminoglycoside or Other \u03b2-Lactam Antibiotics against Common Gram-Negative Pathogens"],"prefix":"10.1159","author":[{"given":"Sheldon M.","family":"Markowitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise J.","family":"Sibilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,8]]},"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/238180","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000238180","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:32:18Z","timestamp":1777476738000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000238180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,8]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000238180","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,8]]}}}