{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:27:38Z","timestamp":1777926458081,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:00:00Z","timestamp":1253145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:00:00Z","timestamp":1253145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>FK 33\u2013824, a potent enkephalin analogue was administered systemically, 0.5\u20135 mg\/kg, to preterm neonatal rabbits. A marked decrease in respiratory frequency as well as irregular breathing and apneic spells was recorded at 5 mg\/kg. Tidal volume was not affected. The enkephalin-induced respiratory depression was restored immediately after naloxone (10 mg\/kg). Based on the results it may be speculated upon whether brain stem enkephalin neurons are involved in the pathogenesis of neonatal transient apnea and irregular breathing.<\/jats:p>","DOI":"10.1159\/000241450","type":"journal-article","created":{"date-parts":[[2009,9,25]],"date-time":"2009-09-25T09:42:34Z","timestamp":1253871754000},"page":"290-294","source":"Crossref","is-referenced-by-count":13,"title":["Transient Apnea after an Enkephalin Analogue in the Preterm Rabbit"],"prefix":"10.1159","author":[{"given":"Thomas","family":"Hedner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Hedner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boinge","family":"Bergman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dag","family":"Lundberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,17]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/241450","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000241450","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:14:58Z","timestamp":1777673698000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000241450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000241450","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,17]]}}}