{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:31:32Z","timestamp":1777926692988,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:00:00Z","timestamp":1253145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:00:00Z","timestamp":1253145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>The endocrine reactivity to a short-term cold exposure (+ 4 \u00b0C during 1 h 30 min) was studied in 8 full-term (FT) and 12 preterm (PT) Limousin \u00d7 Romanov lambs, obtained by oestrogen injections to the ewes; 4 PT animals died (PTD) during the observation period and 8 remained alive (PTA). The plasma cortisol, T&lt;sub&gt;4&lt;\/sub&gt; and T&lt;sub&gt;3&lt;\/sub&gt; levels were lower in PT lambs (particularly in PTD for T&lt;sub&gt;4&lt;\/sub&gt; and T&lt;sub&gt;3&lt;\/sub&gt;) during the first hours of life. Moreover, rectal temperature decreased sharply between birth and 30 min postpartum in the PT group; at this time, plasma T&lt;sub&gt;3&lt;\/sub&gt; levels and rectal temperature were positively related. During cold exposure, the plasma cortisol levels increased in FT lambs, but did not change in the PT group. Moreover, the plasma T&lt;sub&gt;4&lt;\/sub&gt; levels rose slightly in FT animals (+ 12%), increased sharply in PTA lambs (+ 137%), or showed a small decrease in the PTD group (\u2013\u20135%) in which a marked hypothermia occurred; the relative changes in the circulating T&lt;sub&gt;4&lt;\/sub&gt; levels were positively related to the algebraic variations of rectal temperature in PT lambs. However, the changes in the plasma T&lt;sub&gt;3&lt;\/sub&gt; levels did not parallel that of T&lt;sub&gt;4&lt;\/sub&gt; in the three groups of animals, but a positive relationship was observed, in all lambs, between the circulating T&lt;sub&gt;3&lt;\/sub&gt; levels and the rectal temperatures at the end of the cold exposure. These results suggest a reduced sensitivity of the adrenal cortex to stressful conditions in PT lambs. Moreover, they underline the importance of thyroid function for thermoregulation in the newborn lamb, particularly in PT animals.<\/jats:p>","DOI":"10.1159\/000241719","type":"journal-article","created":{"date-parts":[[2009,9,25]],"date-time":"2009-09-25T09:42:34Z","timestamp":1253871754000},"page":"224-233","source":"Crossref","is-referenced-by-count":20,"title":["Endocrine Reactivity (T\n                    <sub>3<\/sub>\n                    , T\n                    <sub>4<\/sub>\n                    , Cortisol) during Cold Exposure in Preterm and Full-Term Lambs"],"prefix":"10.1159","author":[{"given":"G.","family":"Cabello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,17]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/241719","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000241719","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:17:05Z","timestamp":1777673825000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000241719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000241719","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,17]]}}}