{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T08:14:39Z","timestamp":1788423279330,"version":"build-2803163510"},"reference-count":12,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,9,29]],"date-time":"2009-09-29T00:00:00Z","timestamp":1254182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,9,29]],"date-time":"2009-09-29T00:00:00Z","timestamp":1254182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2010]]},"abstract":"<i>Background:<\/i> Sensitivity to Chenopodiaceae is a frequent cause of allergic respiratory diseases in geographic areas where sensitization to <i>Salsola kali<\/i> and <i>Chenopodium album<\/i> has been reported. The objective of this study was to evaluate the pattern of sensitization to 3 <i>Salsola<\/i> species in patients residing on the Mediterranean coast of south-eastern Spain. <i>Methods:<\/i><i>S. kali, S. vermiculata <\/i>and <i>S. oppositifolia<\/i> pollen extracts were prepared. Patients reporting respiratory and\/or cutaneous symptoms were skin prick tested with the 3 <i>Salsola<\/i> extracts. Individuals with positive skin prick tests to at least 1 of the 3 <i>Salsola<\/i> species were included. Specific IgE was determined by direct ELISA. SDS-PAGE and 2-D analysis were conducted to elucidate the protein profile. The allergenic profile was investigated by immunoblot. Inhibition experiments were conducted to establish cross-reactivity between different species. <i>Results:<\/i> 246 patients were included. 237 patients (96.3%) tested positive to <i>S. oppositifolia,<\/i> 189 (76.8%) to <i>S. kali<\/i> and 185 (75.2%) to <i>S. vermiculata<\/i>. Protein profile and immunoblot demonstrated similar patterns in all extracts, except in low-molecular-weight allergens of <i>S. oppositifolia<\/i>. Immunoblot inhibition experiments demonstrated that most high-molecular-weight allergens of <i>S. oppositifolia <\/i>were inhibited by<i> S. kali<\/i> whereas low-molecular-weight allergens were totally inhibited only by <i>C. album<\/i>. <i>Conclusions:<\/i> This study confirms the allergenic importance of other <i>Salsola<\/i> species, especially <i>S. oppositifolia<\/i>. We have demonstrated that the 3 species show a high degree of cross-reactivity, but <i>S. oppositifolia<\/i> shares more allergenic similarities with <i>C. album<\/i> than <i>S. kali<\/i>.<\/jats:p>","DOI":"10.1159\/000242357","type":"journal-article","created":{"date-parts":[[2009,9,28]],"date-time":"2009-09-28T10:11:01Z","timestamp":1254132661000},"page":"199-206","source":"Crossref","is-referenced-by-count":8,"title":["Allergenic Differences among Pollens of Three <i>Salsola<\/i> Species"],"prefix":"10.1159","volume":"151","author":[{"given":"A.","family":"Ferrer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.H.","family":"Larramendi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.J.","family":"Huertas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Pag\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Andreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.L.","family":"Garc\u00eda-Abujeta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"L\u00f3pez-Matas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Carn\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,9,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.114.5.751"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2003.00269.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.2007.02744.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2881%2990101-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000048168"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1157%2F13072921"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaci.2005.11.039"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038%2F227680a0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000082321"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1515%2FBC.2004.089"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186%2F1476-7961-6-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007%2Fs11882-004-0090-5"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/242357","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/242357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:36:01Z","timestamp":1745429761000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000242357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,29]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000242357","archive":["Portico"],"relation":{},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"value":"1018-2438","type":"print"},{"value":"1423-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,29]]}}}