{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:52:00Z","timestamp":1790790720583,"version":"4.1.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>We have used two main techniques to investigate the effect of surfactant therapy on the cerebral circulation in 34 babies. Twenty-one babies were studied using near infrared spectroscopy and 13 had cerebral blood flow measured using a xenon clearance technique. Other measures recorded included amplitude integrated EEG, mean arterial blood pressure and central venous or oesophageal pressure. There was a marked depression in EEG activity lasting for 10\u201320 min after surfactant administration. Cerebral blood volume and cerebral blood flow were maintained in most infants in spite of a fall in mean arterial blood pressure. We conclude that factors other than cerebral ischaemia cause the transient disturbance in electrophysiologic activity.<\/jats:p>","DOI":"10.1159\/000243841","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T05:47:33Z","timestamp":1254462453000},"page":"31-36","source":"Crossref","is-referenced-by-count":27,"title":["Surfactant Administration and the Cerebral Circulation"],"prefix":"10.1159","author":[{"given":"Liselotte","family":"Skov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gorm","family":"Greisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,9,30]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/243841","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000243841","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:26:55Z","timestamp":1777674415000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000243841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000243841","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,30]]}}}