{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:35:44Z","timestamp":1777926944749,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>Continuous hemofiltration is usually regarded as a safe method for controlling fluid overload in neonates presenting acute renal failure. We considered that continuous hemodiafiltration with a hemofilter type especially designed for use in the neonatal period could improve urea removal as compared with hemofiltration. Continuous arteriovenous hemofiltration (CAVH) and hemodiafiltration (CAVHD) were consecutively performed on 7 anesthetized adult rabbits which were given an urea infusion. The hemofilter was a 800-cm2 polysulfone model (Amicon Minifilter Plus). Mean values for physiological and operational parameters were comparable during CAVH and CAVHD, i.e., mean blood pressure (69.6 \u00b1 14.9 and 70 \u00b1 13.1 mm Hg, respectively), arterial oncotic pressure (16.0 \u00b1 2.4 and 16.0 \u00b1 1.7 mm Hg), hematocrit (36.2 \u00b1 5.8 and 36.7 \u00b1 4.4%), protein plasma level (38.9 \u00b1 7.0 and 39.0 \u00b1 6.4 g\/l), urea plasma level (20.6 \u00b1 6.5 and 19.9 \u00b1 7.0 mmol\/l), plasma flow in the hemofilter (7.89 \u00b1 8.48 and 7.12 \u00b1 3.08 ml\/min), and ultrafiltrate rate (1.17 \u00b1 0.49 and 1.73 \u00b1 0.78 ml\/min). CAVHD allowed a significant increase in urea clearance (4.74 \u00b1 4.51 ml\/min) as compared with CAVH (1.23 \u00b1 0.81 ml\/min). These experimental results suggest that CAVHD usefulness should be assessed in neonates presenting acute renal failure.<\/jats:p>","DOI":"10.1159\/000244024","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T06:01:57Z","timestamp":1254463317000},"page":"36-40","source":"Crossref","is-referenced-by-count":9,"title":["Urea Removal by Hemofiltration and Hemodiafiltration"],"prefix":"10.1159","author":[{"given":"J.B.","family":"Gouyon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Petion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Huet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lallemant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,30]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/244024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000244024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:28:53Z","timestamp":1777674533000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000244024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000244024","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,30]]}}}