{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:35:48Z","timestamp":1777926948383,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,9,30]],"date-time":"2009-09-30T00:00:00Z","timestamp":1254268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biol Neonate"],"abstract":"<jats:p>Many studies have shown a greater frequency of apneas in active sleep than in quiet sleep in healthy newborns and infants, both full-term and preterm. The ontogeny of increased apnea during active sleep is related to phasic inhibitory-excitatory central mechanisms occurring during active sleep. Respiratory instability in active sleep can be increased by factors which modify the newborn\u2019s or infant\u2019s homeostasis. We have shown: (1) an increase in body temperature (0.8 \u00b0C) significantly augments periodic breathing in preterm infants at 40 weeks postconceptional age; (2) maternal administration of meperidine is followed by a significant increase in number of apneas during the first hours of life in full-term newborns, but only during active sleep; (3) sleep deprivation induces significantly more obstructive respiratory events in active sleep than in quiet sleep in infants. Active sleep appears to be a risk period for exaggeration of the occurrence of apneas when the newborn\u2019s or infant\u2019s homeostasis is disturbed.<\/jats:p>","DOI":"10.1159\/000244057","type":"journal-article","created":{"date-parts":[[2009,10,2]],"date-time":"2009-10-02T05:47:33Z","timestamp":1254462453000},"page":"231-234","source":"Crossref","is-referenced-by-count":17,"title":["Apnea and Sleep State in Newborns and Infants"],"prefix":"10.1159","author":[{"given":"Cl.","family":"Gaultier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,9,30]]},"container-title":["Biology of the Neonate"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/244057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000244057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:29:14Z","timestamp":1777674554000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000244057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000244057","archive":["Portico"],"relation":{},"ISSN":["0006-3126","1421-9727"],"issn-type":[{"value":"0006-3126","type":"print"},{"value":"1421-9727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,30]]}}}