{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:55:54Z","timestamp":1777866954302,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,10,13]],"date-time":"2009-10-13T00:00:00Z","timestamp":1255392000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,10,13]],"date-time":"2009-10-13T00:00:00Z","timestamp":1255392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatologica"],"abstract":"<jats:p>T-lymphocyte number and function as well as the effect of a thymic hormone on the T-suppressor cell subset were studied in 22 children suffering from psoriasis vulgaris, subdivided into two groups, those with less than 20% of total skin area involved and those with more than 20% of involvement. The T-cell number was lower in the latter group than it was in the first group or in normal controls. There was no significant difference in the functional activity of T cells in the two groups of patients. The number of T-suppressor cells was significantly lower in the psoriatic children than in normal controls, being lowest in the children showing greater skin involvement. THF, a thymic hormone isolated from calves, was found in vitro to induce T-suppressor cells in the peripheral blood of the psoriatic children, suggesting that this hormone may be able to play a role in the treatment of this disease.<\/jats:p>","DOI":"10.1159\/000249427","type":"journal-article","created":{"date-parts":[[2009,10,21]],"date-time":"2009-10-21T09:50:36Z","timestamp":1256118636000},"page":"226-232","source":"Crossref","is-referenced-by-count":0,"title":["In vitro Induction of T-Suppressor Lymphocytes by THF, a Thymic Hormone, in Psoriatic Children"],"prefix":"10.1159","author":[{"given":"Batya","family":"Shohat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Ideses","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"David","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleazar J.","family":"Feuerman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Trainin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,10,13]]},"container-title":["Dermatologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/249427","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000249427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:37:37Z","timestamp":1777541857000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000249427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,13]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000249427","archive":["Portico"],"relation":{},"ISSN":["0011-9075","2571-7197"],"issn-type":[{"value":"0011-9075","type":"print"},{"value":"2571-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,13]]}}}