{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:58:17Z","timestamp":1777867097240,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T00:00:00Z","timestamp":1255564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T00:00:00Z","timestamp":1255564800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatologica"],"abstract":"<jats:p>A report is presented of a 5-year clinical trial during which 78 patients suffering from discoid lupus erythematosus were treated with 1-percent betametasone 17-valerate in an oil\/water emulsion cream. In 10 cases, local treatment had to be supplemented by the oral administration of chloroquine for shorter or longer periods. On the whole, this therapy represented a great advance, the majority of the patients being kept completely or almost completely free of symptoms by means of local treatment alone. No steroid-induced atrophy of the epidermis was observed. It should be emphasized that the patients were checked at intervals of a few months and were carefully instructed as to the procedure to be followed during the local treatment.<\/jats:p>","DOI":"10.1159\/000251488","type":"journal-article","created":{"date-parts":[[2009,10,21]],"date-time":"2009-10-21T09:50:36Z","timestamp":1256118636000},"page":"65-68","source":"Crossref","is-referenced-by-count":11,"title":["Treatment of Discoid Lupus Erythematosus with Betametasone-Valerate Cream 1%"],"prefix":"10.1159","author":[{"given":"F.","family":"Reymann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,10,15]]},"container-title":["Dermatologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/251488","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000251488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:49:31Z","timestamp":1777542571000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000251488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,15]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000251488","archive":["Portico"],"relation":{},"ISSN":["0011-9075","2571-7197"],"issn-type":[{"value":"0011-9075","type":"print"},{"value":"2571-7197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,15]]}}}