{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:39:41Z","timestamp":1790894381102,"version":"4.1.0"},"reference-count":24,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dev Neurosci"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Birth asphyxia can result in sensory impairment, learning and memory deficits without gross brain injury and severe motor deficits. We developed a model of birth asphyxia resulting in mild neurological injury and cognitive impairment using a long-gestation species with precocial fetal development. Spiny mice &lt;i&gt;(Acomys cahirinus)&lt;\/i&gt; underwent caesarean-section delivery or 7.5 min of asphyxia at 37 days gestational age (term is 39 days). Brain histology was examined at 1 and 7 days of age, and behaviour was evaluated to 28 days of age. Asphyxiated offspring showed significant impairment in non-spatial memory and learning tasks, accompanied by central nervous system inflammation and increased apoptotic cell death but without the presence of large necrotic or cystic lesions.<\/jats:p>","DOI":"10.1159\/000251907","type":"journal-article","created":{"date-parts":[[2009,10,23]],"date-time":"2009-10-23T14:20:24Z","timestamp":1256307624000},"page":"523-535","source":"Crossref","is-referenced-by-count":18,"title":["Neuropathology and Functional Deficits in a Model of Birth Asphyxia in the Precocial Spiny Mouse &lt;i&gt;(Acomys cahirinus)&lt;\/i&gt;"],"prefix":"10.1159","volume":"31","author":[{"given":"Lisa C.","family":"Hutton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udani","family":"Ratnayake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Shields","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,10,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00431-007-0437-8"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.2005.092445"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1080%2F00016340801996622"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.2004.067520"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.109.1.26"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136%2Ffn.86.1.F16"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3476%2889%2980132-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1440-1789.2002.00438.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1023%2FB%3AJOBB.0000041770.00567.4f"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.brainres.2006.08.030"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0163-1047%2885%2991337-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2007.10.790"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ajog.2007.06.035"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000105475"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2F0166-4328%2888%2990157-X"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2174%2F1568006043481284"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.brainresbull.2008.10.007"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00537801"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00221-007-1186-7"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1901%2Fjeab.1958.1-341"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016%2F0149-7634%2879%2990012-5"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1159%2F000155218"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.bbr.2005.10.010"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2FS0024-3205%2899%2900678-5"}],"container-title":["Developmental Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/251907","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/251907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T21:51:36Z","timestamp":1745445096000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000251907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":24,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2009,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000251907","archive":["Portico"],"relation":{},"ISSN":["0378-5866","1421-9859"],"issn-type":[{"value":"0378-5866","type":"print"},{"value":"1421-9859","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}