{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T15:54:24Z","timestamp":1783698864984,"version":"3.55.0"},"reference-count":23,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2009]]},"abstract":"<i>Purpose:<\/i> To investigate the possible prognostic factors of survival outcomes in patients with granulocytic sarcoma (GS). <i>Methods:<\/i> We retrospectively investigated the prognostic factors determining survival in 24 patients with GS using Kaplan-Meier survival analysis followed by log rank tests. We evaluated gender, age, location, GS antedating leukemia, underlying disorders, treatment type and stem cell transplantation. <i>Results:<\/i> The 5-year survival rate for the patients with GS was 21%. The patients undergoing chemotherapy had a significantly longer survival time compared to those who did not (p = 0.0009). We found no difference in the 5-year survival rate among the patients undergoing chemotherapy combined with radiation or surgery. Patients with chronic myelogenous leukemia and myelodysplastic disorders had worse survival rates (p = 0.0028). <i>Conclusion:<\/i> Early diagnosis with biopsy and early chemotherapy can improve survival outcome. Local radiation or surgery can improve symptoms but does not influence survival outcomes.<\/jats:p>","DOI":"10.1159\/000253592","type":"journal-article","created":{"date-parts":[[2009,10,30]],"date-time":"2009-10-30T13:33:43Z","timestamp":1256909623000},"page":"238-246","source":"Crossref","is-referenced-by-count":122,"title":["Prognostic Factors of Treatment Outcomes in Patients with Granulocytic Sarcoma"],"prefix":"10.1159","volume":"122","author":[{"given":"Tsung-Yu","family":"Lan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Tsamn","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hwei-Fang","family":"Tien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Sen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2009,10,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fpbc.21190"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.cancergencyto.2008.04.016"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.bmt.1703316"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1080%2F10245330600702893"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9343%2891%2990559-G"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1080%2F10428190600967196"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00000478-199710000-00005"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2559.1999.00651.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2820001225%2990%3A6%3C364%3A%3AAID-CNCR7%3E3.0.CO%3B2-1"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0899-7071%2801%2900388-6"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2Fs12185-008-0227-8"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00000478-199310000-00006"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819861215%2958%3A12%3C2697%3A%3AAID-CNCR2820581225%3E3.0.CO%3B2-R"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.10399"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.leu.2402958"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291097-0142%2820000415%2988%3A8%3C1939%3A%3AAID-CNCR24%3E3.0.CO%3B2-Z"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00256-007-0314-6"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2F0730-725X%2893%2990421-9"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016%2FS0090-4295%2802%2901750-8"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.leu.2404491"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1200%2FJCO.2007.15.6315"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%2819810915%2948%3A6%3C1426%3A%3AAID-CNCR2820480626%3E3.0.CO%3B2-G"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.onc.1207727"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/253592","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/253592","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T21:09:06Z","timestamp":1745442546000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000253592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":23,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2009,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000253592","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"value":"0001-5792","type":"print"},{"value":"1421-9662","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}