{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T11:59:40Z","timestamp":1762430380310,"version":"3.40.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T00:00:00Z","timestamp":1257292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,11,4]],"date-time":"2009-11-04T00:00:00Z","timestamp":1257292800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2010]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Congenital infections are associated with a wide spectrum of clinical symptoms, including lenticulostriate vasculopathy (LSV). &lt;i&gt;Objective:&lt;\/i&gt; To determine the relationship between LSV and congenital infections, as diagnosed by TORCH serology and viral culture for cytomegalovirus (CMV). &lt;i&gt;Methods:&lt;\/i&gt; All neonates with LSV admitted to our neonatal intensive-care unit from 2004 to 2008 were included in the study. Results of maternal and neonatal TORCH testing were evaluated. &lt;i&gt;Results:&lt;\/i&gt; During the study period, cranial ultrasound scans were performed in 2,088 neonates. LSV was detected in 80 (4%) neonates. Maternal and\/or neonatal serological TORCH tests were performed in 73% (58\/80) of cases. None of the mothers or infants (0 of 58) had positive IgM titres for &lt;i&gt;Toxoplasma&lt;\/i&gt;, rubella, CMV or herpes simplex virus. Additional urine culture for CMV was performed in 38 neonates. None of the infants (0 of 38) had a positive CMV urine culture test. &lt;i&gt;Conclusions:&lt;\/i&gt; Routinely applied efforts to diagnose congenital infections in cases presenting with LSV have a poor yield. Routine TORCH screening in neonates with LSV cases should only be regarded as mandatory once well-designed studies demonstrate a clear diagnostic benefit.<\/jats:p>","DOI":"10.1159\/000255166","type":"journal-article","created":{"date-parts":[[2009,11,6]],"date-time":"2009-11-06T11:08:48Z","timestamp":1257505728000},"page":"274-278","source":"Crossref","is-referenced-by-count":24,"title":["Is Routine TORCH Screening Warranted in Neonates with Lenticulostriate Vasculopathy?"],"prefix":"10.1159","volume":"97","author":[{"given":"E.P.","family":"de Jong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Lopriore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.C.T.M.","family":"Vossen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.J.","family":"Steggerda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.B.","family":"Te Pas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.C.M.","family":"Kroes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.J.","family":"Walther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,11,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002470000322"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Ffn.88.5.F410"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02012490"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1080%2F08035250510041150"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00247-003-0948-z"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2007-993878"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2F0887-8994%2894%2990042-6"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0887-8994%2800%2900146-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002%2Fjmv.20325"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jcv.2008.02.004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0264-410X%2802%2900587-X"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2383041109"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.1242"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2000-9288"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/255166","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/255166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T21:25:09Z","timestamp":1745443509000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000255166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,4]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2010,3,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000255166","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"type":"print","value":"1661-7800"},{"type":"electronic","value":"1661-7819"}],"subject":[],"published":{"date-parts":[[2009,11,4]]}}}