{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T02:31:37Z","timestamp":1777343497577,"version":"3.51.4"},"reference-count":20,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; The aim of this work was to compare the prevalence of the metabolic syndrome (MS) and its components between a group of autosomal-dominant polycystic kidney disease (ADPKD) patients with normal kidney function and no prior diagnosis of diabetes and healthy controls. &lt;i&gt;Methods:&lt;\/i&gt; Forty-nine patients with ADPKD (age 35.9 \u00b1 11.1 years) with serum creatinine &lt;1.35 mg\/dl and 50 healthy controls (36.7 \u00b1 9.2 years) were enrolled for the study. Physical examination, basic laboratory measurements and oral glucose tolerance test were performed in all subjects. &lt;i&gt;Results:&lt;\/i&gt; In the group of ADPKD patients, when compared to controls, the following values were significantly higher: waist-to-hip ratio (0.84 \u00b1 0.09 vs. 0.81 \u00b1 0.10, p = 0.046), systolic blood pressure (133.9 \u00b1 19.8 vs. 122.2 \u00b1 14.9 mm Hg, p = 0.0023), diastolic blood pressure (92.9 \u00b1 12.4 vs. 82.9 \u00b1 9.3 mm Hg, p &lt; 0.0001), fasting glycemia (91.6 \u00b1 10.5 vs. 84.5 \u00b1 9.2 mg\/dl, p = 0.04), and HbA&lt;sub&gt;1C&lt;\/sub&gt; (5.41 \u00b1 0.35 vs. 5.28 \u00b1 0.33%, p = 0.06, borderline significance). Adult Treatment Panel III criteria of MS were fulfilled by 14% of patients and 14% of controls, while International Diabetes Federation criteria were fulfilled by 22% of patients and 20% of controls, without any significant difference between the groups. &lt;i&gt;Conclusion:&lt;\/i&gt; The presence of ADPKD with normal kidney function is associated with components of MS such as hypertension, abdominal obesity and higher fasting glycemia.<\/jats:p>","DOI":"10.1159\/000260042","type":"journal-article","created":{"date-parts":[[2009,11,24]],"date-time":"2009-11-24T08:28:15Z","timestamp":1259051295000},"page":"405-410","source":"Crossref","is-referenced-by-count":17,"title":["Metabolic Syndrome Components in Patients with Autosomal-Dominant Polycystic Kidney Disease"],"prefix":"10.1159","volume":"32","author":[{"given":"Maria","family":"Pietrzak-Nowacka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Safranow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"El\u017cbieta","family":"Byra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Bi\u0144czak-Kuleta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Ciechanowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazimierz","family":"Ciechanowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,11,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.07-2147"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000051257"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.amjhyper.2004.06.020"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2F14.5.1244"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1523-1755.2005.67132.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F01.tp.0000248759.37146.3d"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2F17.5.887"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.arcmed.2007.10.003"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.arcmed.2005.07.009"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.37.12.1595"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291096-9136%28199807%2915%3A7%3C539%3A%3AAID-DIA668%3E3.0.CO%3B2-S"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.285.19.2486"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1997.360"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2894%2992026-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.21.12.2191"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1053%2Fmeta.2002.28970"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159%2F000180580"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.47.5.699"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1681%2FASN.2005121332"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1997.260"}],"container-title":["Kidney and Blood Pressure Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/260042","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/260042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T21:25:40Z","timestamp":1745443540000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000260042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":20,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2010,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000260042","archive":["Portico"],"relation":{},"ISSN":["1420-4096","1423-0143"],"issn-type":[{"value":"1420-4096","type":"print"},{"value":"1423-0143","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}