{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T01:27:21Z","timestamp":1777771641473,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2009,11,19]],"date-time":"2009-11-19T00:00:00Z","timestamp":1258588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2009,11,19]],"date-time":"2009-11-19T00:00:00Z","timestamp":1258588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"abstract":"<jats:p>The amounts of loosely bound fluoride (F) deposited on human enamel by 4-min and 2-hour treatments with either acidulated phosphate fluoride (APF) or a monocalcium phosphate monohydrate and sodium hexafluorosilicate (MCPM-SHFS)-containing gel were measured with the use of a constant-composition F washing method. Enamel biopsies conducted before treatment and after washing were used to determine the firmly bound F uptake. The results showed that the MCPM-SHFS treatments produced significantly more loosely bound F than did the APF treatments. The 4-min treatment with either APF or MCPM-SHFS did not produce significant firmly bound F deposition, but the 2-hour treatments did, with that produced by MCPM-SHFS being significantly greater. The MCPM-SHFS gel, which had the same F content as APF and which may be applied to the proximal tooth surfaces in vivo without the use of a tray, has the potential to be more efficacious than APF because it deposits greater amounts of both loosely bound and firmly bound F.<\/jats:p>","DOI":"10.1159\/000261462","type":"journal-article","created":{"date-parts":[[2009,11,24]],"date-time":"2009-11-24T03:28:15Z","timestamp":1259033295000},"page":"321-327","source":"Crossref","is-referenced-by-count":9,"title":["Deposition of Loosely Bound and Firmly Bound Fluorides on Tooth Enamel by an Acidic Gel Containing Fluorosilicate and Monocalcium Phosphate Monohydrate"],"prefix":"10.1159","author":[{"given":"S.","family":"Takagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Chow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.A.","family":"Sieck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2009,11,19]]},"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000261462","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:52:24Z","timestamp":1777481544000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000261462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,19]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000261462","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,19]]}}}